Symbol
Name
ID

Ptk2
PTK2 protein tyrosine kinase 2
MGI:95481

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Mouse Phenotypes

abnormal blood vessel morphology

abnormal dorsal aorta morphology

abnormal vitelline artery morphology

abnormal aorta morphology

abnormal vascular endothelial cell morphology

abnormal capillary morphology

abnormal placenta vasculature

abnormal vascular development

abnormal vascular regression

abnormal vascular branching morphogenesis

decreased angiogenesis

abnormal vascular endothelial cell development

abnormal vitelline vasculature morphology

absent vitelline blood vessels

disorganized yolk sac vascular plexus

dilated vasculature

abnormal myocardium layer morphology

abnormal myocardial fiber morphology

disorganized myocardium

thick myocardium

abnormal heart development

abnormal mesocardium morphology

delayed heart development

abnormal heart morphology

abnormal endocardium morphology

cardiac hypertrophy

dilated heart left ventricle

cardiac interstitial fibrosis

abnormal blood circulation

hemorrhage

liver hemorrhage

absent heartbeat

increased vascular permeability

Availability

Mouse Genotype

Ptk2^tm1.1Itl/Ptk2^tm1.1Itl

Ptk2^tm1Heen/Ptk2^tm1Heen

Ptk2^tm1Imeg/Ptk2^tm1Imeg

Ptk2^tm1Imeg/Ptk2⁺

Myl2^tm1(cre)Krc/Myl2⁺
Ptk2^tm1.1Guan/Ptk2^tm1.1Guan (conditional)

Ptk2^tm1.1Guan/Ptk2^tm1.1Guan
Tg(Tek-cre)12Flv/0 (conditional)

Ptk2^tm1Lfr/Ptk2^tm1Lfr
Tg(Tek-cre)1Rwng/0 (conditional)

Ptk2^tm1.1Guan/Ptk2^tm1.2Guan
Tg(Tek-cre)12Flv/0 (conditional)

Ptk2^tm2.1Guan/Ptk2^tm1.1Guan
Tg(Tek-cre)12Flv/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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